Passive immunization (oral) with plant produced antibodies
- As a proof of concept we have developed antibodies against F4 fimbriae of Escherichia coli in seeds of Arabidopsis.
- Plant F4 Abs can provide passive immunity to pigs and protect them against infection with F4+ ETEC and development of diarrhoea
- The technology can easily be transferred from Arabidopsis to other crops that are suitable feed ingredients (e.g. soybean).
- Plant based F4 Abs can thus provide a valuable alternative for antibiotics and avoid huge financial losses for the farmer.