We have developed a codon-optimized, MOMP-based DNA vaccine that significantly protects birds (Psittaciformes) against a high challenge with the zoonotic pathogen Chlamydophila psittaci (Cp psittaci).
- can be used in the presence of circulating antibodies against Cp psittaci
- induces a high cellular immune response, which is more important for protection against the intracellular pathogen than high antibody titers
- can be useful for prevention of the infection (e.g. in breeding facilities or zoos)
The vaccine can significantly reduce the infection of people that are in contact with Psittaciformes like breeders, veterinarians, pet bird owners but also the public at large.