Services

In vitro and in vivo models and services for the development and validation of innovative therapeutics and vaccines

PROVAXS Services : from service to science and innovation

PROVAXS Services is a unique platform at Ghent University that offers high quality animal models and related services for your research and development projects. Our models and services can be either used for veterinary studies in the target animal or for non-clinical studies for human medicines.

The added value we bring to your project is based on several assets :

  • A broad portfolio of solid and well validated animal models in different species
  • Services are provided by a dedicated and highly qualified team and in line with industrial standards
  • Science at your service
    • We offer a selection of animal models that are all based on the strong expertise of the scientists and researchers of Ghent University who developed them
    • UGent scientists provide academic back up to assist in the finetuning of the protocol, the interpretation of the results and the writing of an expert report
  • High flexibility to adapt the existing models to the needs of the client
  • Performance of animal models can be combined with other activities like diagnostic services, in vitro models and field trials to support vaccine and drug testing

Description

At PROVAXS Services academic expertise and industrial product development thus touch each other by use of the in vitro and in vivo models that we offer.

The intensive interaction with our scientists can lead to more intensive and fruitful collaborations resulting in new innovations that can improve animal health.

Since many years our models and services have proven their value for both fundamental research and for testing of new or marketed products. Today we offer :

  • animal facilities for a wide range of animal species (swine, cattle, poultry, goat, sheep, horse, dog, cat, rabbit, ferret, guinea pig and mice)
  • studies that comply with currently applicable scientific, legal, regulatory, and ethical requirements and guidelines
  • pharmacokinetic, bio-availability, residue and safety studies and bio-analysis with respect to the OECD and the EU principles of Good Laboratory Practice

Our infrastructure offers up to 50 separate animal units ranging in size from 10 up to 60m2 at biosafety level (BSL)2 and 3 animal units (350m2) at BSL3. All rooms are designed to allow housing of different animal species and, as such, allow maximum flexibility. The facilities meet the highest standards in view of biosafety (including sophisticated air-handling units and, for the BSL3-units, effluent decontamination and tissue digestion) and are in compliance with the latest ethical guidelines (KB29052013 and Directive 2010/63/EU).

Our Services

  • are valuable in R&D- and registration programs for veterinary pharma and/or feed additives or for non-clinical research for human pharma.
  • cover the whole track from screening and selection of lead compounds/biologicals to efficacy studies and validation of the selected candidate:
    • in vitro screening tests
    • in vitro/in vivo: e.g. intestinal loop model (pig), caecal loop model (chicken), ex vivo explants
    • in vivo: challenge models, seeder models, field studies
  • are tailor made : different aspects of our expertise can be combined according to your needs
    • Academic and regulatory expertise
    • BSL2/3 animal facilities
    • BSL2/3 laboratories
    • Field studies

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Overview animal models

Overview of all our models per animal species and pathogens

Overview