Entry portal trough the intestinal barrier

Our technology enables controlled transfer of biological compounds through the intestinal (mucosal) barrier

Via selective transcytosis through the intestinal barrier various functions at the level of the intestinal epithelium and beyond can be modulated

antigens can be efficiently presented to the gut associated lymphoid tissue (GALT) leading to a protective mucosal immune response
drugs or drug-containing (nano-)particles can be transferred and delivered across the intestinal barrier

Blocking the gateway through the intestinal barrier can reduce the colonisation of and passage through the intestinal epithelium by bacteria, more specifically by E. coli (F4 or K88 positive) , well known for causing diarrhoea in animals and man.

Please download the Technology Offer and the publication in Mucosal Immunology – Nature for more information.
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